Human Biomonitoring

Recent advances in analytical chemistry allow us to better detect both natural and synthetic substances in human tissues through an advanced technology called biomonitoring. This promising public health tool can help us better understand human exposure to a wide range of substances. Biomonitoring is defined as one method for assessing human exposure to chemicals by measuring the chemicals or their metabolites in human tissues or specimens, such as blood or urine. Biomonitoring has identified and confirmed human exposure to environmental substances, such as the presence of lead in children’s blood. Biomonitoring can be applied in various ways, including evaluation of the presence of chemicals in body tissues, and to track spatial variation and temporal trends in chemical exposure. Biomonitoring may also be helpful in identifying at-risk populations. However, human biomonitoring data requires careful interpretation. In particular, the presence of an environmental chemical in a person’s blood or urine does not by itself mean that the chemical causes disease an environmental chemical in a person’s blood or urine does not by itself mean that the chemical
causes disease. Human biomonitoring is a tool with great potential to contribute to our understanding of human exposure to environmental substances. However, there is a need for consideration of ethical issues relating to the collection of human tissues for biomonitoring purposes at all stages of a biomonitoring program. Effective communication is among the biggest challenges currently in the field. Research is needed to support the interpretation of biomonitoring results. It is critical that biomonitoring study designs be carefully constructed in order to ensure that informative biomonitoring results be obtained.