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Institute of Population Health
R. Samuel McLaughlin Centre for Population Health Risk Assessment

PAHO/WHO COLLABORATING CENTRE IN POPULATION
HEALTH RISK ASSESSMENT

Symposium on International Implications of the U.S. National Research Council Report on Toxicity Testing in the 21st Century: Challenges and Opportunities in Implementation

University of Ottawa, Desmarais Building, 55 Laurier St. East
 Room 1150
June 29-30, 2009

The Johns Hopkins Bloomberg School of Public Health, Center for Alternatives to Animal Testing (Baltimore, Maryland, USA) and the McLaughlin Centre for Popultion Health Risk Assessment at the University of Ottawa organized this symposium, which examined from an international perspective the scientific, risk assessment and implementation challenges and opportunities generated by the vision containted in the US National Research Council’s Toxicity Testing report.

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View List of Participants
*A workshop report will be posted at a later time

Day 1 – Monday, June 29, 2009

8:45am
Introduction and Welcome
Daniel Krewski, University of Ottawa
Paul Locke, Johns Hopkins Bloomberg School of Public Health, Center for Alternatives to Animal Testing

Maria Trainer, Council of Canadian Academies

9:00am
Keynote Address: Current State of the Science of Toxicity Testing
Thomas Hartung, Johns Hopkins Bloomberg School of Public Health, Center for Alternatives to Animal Testing

9:20am
Response and Comment to Keynote Address
Melvin Andersen, The Hamner Institute for Health Sciences

Raymond Tice, US NIEHS

11:00am
Keynote Address Current State of the Science in Chemical Risk Assessment
Bette Meek, McLaughlin Centre for Population Health Risk Assessment, University of Ottawa

11:20am
Response and Comment to Keynote Address
Richard Judson,US EPA, National Center for Computational Toxicology

Greg Paoli, Risk Sciences International

1:30pm
Pannel Discussion: Challenges in International Implementation of Risk Assessment and Testing Guidelines
Vicki Dellarco, U.S. EPA

David Blakey,  Environmental Health Science and Research Bureau, Health Canada

Gail Charnley, HealthRisk Strategies

Manfred Liebsch, Federal institute for Risk Assessment, ZEBET

4:15pm
The NAS Report in 2007 and Today: Progress and New Opportunities
Daniel Krewski, McLaughlin Centre for Population Health Risk Assessment, University of Ottawa

7:00pm
Economic and Cost-Benefit Aspects of Implementing New Risk Assessment Guidelines in Canada
John Giraldez, Treasury Board of Canada

Day 2 -  Tuesday June 30, 2009

8:40 am
Overview – Key Issues from Day 1 of Symposium
Daniel Krewski, McLaughlin Centre for Population Health Risk Assessment, University of Ottawa

9:00 am
International Implementaition of the NAS Vision for Toxicity Testing: Are Changes in Regulatroy Practice Needed? 
E. Donald Elliott, Willkie Farr & Gallagher LLP and Professor (Adjunct) of Law, Yale Law School

9:20 am
Response and Comment
Theresa McClenaghan, Canadian Environmental Law Association

Bruce Myers, Environmental Law Institute 

11:00 am
Panel Discussion: Challenges in Implementing Consistent Public Health and Environmental Regulatory Policies
Claire Franklin, The McLaughlin Centre for Population Health Risk Assessment, University of Ottawa and the LifeLine Group

Lynda Collins, Faculty of Law, University of Ottawa

Karen Lloyd, Chemicals, Air and Water Directorate, Health Canada

12:00 pm
Summary: the Path Forward
Paul Locke, Johns Hopkins Bloomberg School of Public Health, Center for Alternatives to Animal Testing

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Other relevant documents and links for Toxicity Testing in the 21st
U.S. Environmental Protection Agency: The U.S. Environmental Protection Agency's Strategic Plan for Evaluating the Toxicity of Chemicals.
Anderson and Krewski: Forum Series, Part I: Toxicity Testing in the 21st Century: Bringing the Vision to Life
Krewski et al: Toxicity Testing in the 21st Century
Committee on Toxicity and Assessment of Environmental Agents: Toxicity testing in the Twenty-first Century: A Vision and a Strategy
National Institute of Environmental Health Sciences: National Toxicology Program (NTP) High Throughput Screening Initiative
NTP, NGCE and EPA: High Throughput Screening, Toxicity Pathway Profiling, and Biological Interpretation of Findings.
Kavlock, Austin and Tice: Toxicity Testing in the 21st Century: Implications for Human Health Risk Assessment.
Xia et al: Compound Cytotoxicity Profiling Using Quantitative High-Throughput Screening.
Environmental Law Instititue: About ELI
Environmental Law Institute: Implementing Alternatives to Animal Testing under U.S. Toxics and Pesticide Laws

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